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  1. May 21, 2022 · A hypothesis is an educated guess or statement about the relationship between 2 or more variables 2,3. Scientific hypothesis generation is a critical step in scientific research …

  2. Hypothesis-generating analysis of mutational signatures in …

    Oct 9, 2025 · Clock-like signatures show associations with parental and patient age as well as SES, potentially indicating some age-dependent differences. These results should inform …

  3. Hypothesis-driven patterns of intracranial exploration in

    Jul 22, 2024 · Using semiological observations and a detailed cytoarchitectonic analysis, we propose a novel hypothesis classification system of four hypotheses in TLE and describe this …

  4. Vancomycin Exposure is Associated with Protection from Acute …

    4 days ago · To test this hypothesis we assessed the a) association between vancomycin exposure and aGVHD b) association between stool Enterococcus abundance and aGVHD c) …

  5. Drivers of protective behaviours during epidemics | medRxiv

    2 days ago · Our results provide quantitative evidence about the main drivers of mask wearing behaviours, provide a reproducible method to test their impact on other protective behaviours, …

  6. Trauma Exposure, PTSD, and Methylation of the Blood Brain …

    4 days ago · Future research is needed to test the mechanistic hypothesis that trauma exposure and chronic PTSD alter CLDN5 DNAm, lead to increased BBB permeability and allow for …

  7. Embryonic Germ Layer Origin as a Potential Determinant of Cancer ...

    Jun 17, 2025 · This systematic review examines the hypothesis that therapeutic efficacy correlates with the developmental origin of neoplasms, specifically proposing differential …

  8. Hypothesis test of arbitrary parametric structure in a generalized ...

    May 13, 2025 · Follow this preprint Hypothesis test of arbitrary parametric structure in a generalized additive model Yihe Yang, Xiaofeng Zhu doi: …

  9. COVID-19 Origins: Quantifying Scientific Consensus Amid Political ...

    Jun 12, 2025 · The lab leak hypothesis, which involves an escape of the virus from WIV laboratory in Wuhan, China and the natural origin hypothesis possible through an intermediate host.

  10. Neuroimaging-derived brain endophenotypes link molecular …

    4 days ago · In conclusion, this gene prioritization and hypothesis-generating framework demonstrates that biologically characterized neuroimaging endophenotypes, when integrated …