The gyrase motif reflects wrapping of DNA around the enzyme complex and DNA flexibility. It contains two periodic regions in which GC-rich islands are alternated with AT-rich patches by a period close to …

Aug 3, 2023 · Prokaryotic topoisomerase II, also known as DNA gyrase, is the only topoisomerase that introduces negative supercoils into DNA thus far. DNA topoisomerases are a class of enzymes that …

Gyrase is an enzyme that plays a part in managing the complex structure of DNA within cells. Its primary role involves controlling DNA’s shape and preventing tangles.

Dec 1, 2024 · 4. DNA gyrase structure DNA gyrase is a heterotetramer composed of two gyrA and two gyrB subunits, organized in a two-fold symmetric three-domain structure. ATP-binding and hydrolysis …

The meaning of GYRASE is a bacterial enzyme that catalyzes the breaking and rejoining of bonds linking adjacent nucleotides in circular DNA to generate supercoiled DNA helices.

DNA gyrase is an essential bacterial enzyme that catalyzes the ATP-dependent negative super-coiling of double-stranded closed-circular DNA. Gyrase belongs to a class of enzymes known as …

May 6, 2025 · DNA gyrase is an essential bacterial enzyme that introduces negative supercoiling into DNA, facilitating processes such as replication, transcription, and recombination.

Jul 23, 2025 · DNA gyrase is an enzyme found in bacteria and some archaea, playing a unique role in their cellular processes. It belongs to a specialized group of enzymes known as type II topoisomerases.

DNA Gyrase is a crucial bacterial enzyme that introduces negative supercoils into DNA, facilitating replication and serving as a key antibiotic target.

Gyrase breaks and rejoins both strands of DNA simultaneously and enzymes like gyrase are classified as type 2 topoisomerases. Today, there are hundreds of topoisomerase being studied in all forms of life.