Cell reprogramming: methods, mechanisms and applications - PMC
Apr 9, 2025 · This review summarizes the recent advances in cell reprogramming mediated by transcription factors or chemical molecules, followed by elaborating on the important roles of …
Reprogramming - Wikipedia
In biology, reprogramming refers to erasure and remodeling of epigenetic marks, such as DNA methylation, during mammalian development or in cell culture. [1] Such control is also often …
New steps forward in cell reprogramming - Harvard University
In addition to problems of safety, reprogramming thus far been a very inefficient process – only about one in every 1,000 mature cells is successfully reprogrammed.
Reprogramming - Latest research and news | Nature
Oct 17, 2025 · Cell reprogramming is the process of reverting mature, specialised cells into induced pluripotent stem cells. Reprogramming also refers to the erasure and re …
How Scientists Reprogram Cells to Research Diseases | ISCRM
In 2006, scientists led by Shinya Yamanaka at Kyoto University in Japan pioneered a new technology, known as induced pluripotent stem cells, or iPSC for short. This breakthrough …
What is Cell Reprogramming and What Does It Mean?
Cell reprogramming is the act of reverting mature, specialised cells into induced pluripotent stem cells, also known as iPS cells. This process requires a stem or progenitor cell intermediary.
Therapeutic Reprogramming toward Regenerative Medicine
Feb 5, 2025 · Therapeutic reprogramming represents a transformative paradigm in regenerative medicine, developing new approaches in cell therapy, small molecule drugs, biologics, and …
Induced Pluripotent Stem Cells: Reprogramming Platforms and ...
This review discusses the scientific framework that led to the reprogramming of induced pluripotent stem cells (iPSCs), the roles of the OSKM in reprogramming the mature …
Chemical reprogramming for cell fate manipulation: Methods ...
Aug 24, 2023 · Chemical reprogramming offers an unprecedented opportunity to control somatic cell fate and generate desired cell types including pluripotent stem cells for applications in …
Blocking nuclear receptor Nr4a3 unlocks the senescence barrier to ...
Nov 14, 2025 · Blocking senescence regulator Nr4a3 improves fibroblast-to-cardiomyocyte reprogramming and heart repair after injury.