RMD Open1d
Holistic approaches in systemic lupus erythematosus: do physicians avoid addressing difficult-to-treat but highly relevant symptoms?
Despite advancements in the management of systemic lupus erythematosus (SLE), patients experience poor health-related quality of life (hrQoL) and premature death due to disease severity and treatment ...
rmdopen.bmj4d
Diagnostic and prognostic role of synovial tissue analysis in juvenile idiopathic arthritis: a monocentric study
Objectives This study investigates the diagnostic role of synovial tissue analysis in children presenting with arthritis and assesses its prognostic significance to predict clinical outcome in ...
rmdopen.bmj5d
Cartilage-gut-microbiome axis: a new paradigm for novel therapeutic opportunities in osteoarthritis
DNA of gut microbiota can be found in synovium of osteoarthritis and rheumatoid arthritis. This finding could result from the translocation of still alive bacteria from gut to joints through blood, ...
rmdopen.bmj5d
New pro-inflammatory cytokine IL-40 is produced by activated neutrophils and plays a role in the early stages of seropositive rheumatoid arthritis
Objective Interleukin (IL)-40 is a new cytokine related to immune system function and malignancies. Recently, an association of IL-40 with rheumatoid arthritis (RA) and externalisation of neutrophil ...
rmdopen.bmj5d
Procedures for the content, conduct and format of EULAR/PReS paediatric musculoskeletal ultrasound courses
Background Despite the worldwide increasing request of education on paediatric musculoskeletal ultrasound (PedMSUS), content, conduct and format of PedMSUS courses have never been internationally ...
rmdopen.bmj5d
Machine learning identifies risk factors associated with long-term opioid use in fibromyalgia patients newly initiated on an opioid
Objectives Fibromyalgia is frequently treated with opioids due to limited therapeutic options. Long-term opioid use is associated with several adverse outcomes. Identifying factors associated with ...
rmdopen.bmj5d
Spontaneous resolution of acute gout: mechanisms and therapeutic targets
3 Jiangxi Provincial Clinical Research Center for Rheumatic and Immunologic Diseases, Nanchang, People's Republic of China 4 Key Laboratory of Rheumatology and Immunology, Health Commission of Jiangxi ...
rmdopen.bmj6d
Prevalence and consequences of psoriasis in recent axial spondyloarthritis: an analysis of the DESIR cohort over 6 years
Objectives The consequences of psoriasis associated to axial spondyloarthritis (axSpA) are unclear. The objectives were to determine the prevalence and the consequences of psoriasis in recent axSpA ...
rmdopen.bmj6d
Changes in ankylosing spondylitis incidence, prevalence and time to diagnosis over two decades
Objectives To assess changes in ankylosing spondylitis (AS) incidence, prevalence and time to diagnosis, between 1998 and 2017. Methods Using UK GP data from the Clinical Practice Research Datalink, ...
rmdopen.bmj7d
Humoral and cellular SARS-CoV-2 vaccine responses in patients with giant cell arteritis and polymyalgia rheumatica
Objectives Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are overlapping autoinflammatory diseases affecting people over 50 years. The diseases are treated with immunosuppressive drugs ...
rmdopen.bmj7d
Hyaluronan for knee osteoarthritis: an updated meta-analysis of trials with low risk of bias
Background The effectiveness of intra-articular hyaluronic acid (IAHA) injection for knee osteoarthritis (KOA) is debated. Objectives To evaluate the effect of IAHA for patients with KOA by analysing ...
RMD Open9d
Getting prepared for the silver wave: challenges in conducting rheumatic and musculoskeletal disease research in older adults
Research in older adults diagnosed with rheumatic and musculoskeletal diseases (RMDs) comes with unique challenges, as these patients often face consequences of ageing, such as multimorbidity, ...