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Small ubiquitin-like modifiers (SUMO) and ubiquitin are frequent post-translational modifications of proteins that play pivotal roles in all cellular processes. We previously reported mass ...
The ubiquitin ligase LNX (ligand of numb-protein X) can ubiquitinate Numb, preventing internal sequestration of Notch, resulting in enhanced downstream Notch signaling. 13 The ubiquitin ligase Itch ...