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Cryo-EM structure of the MmpL5-MmpS5-AcpM complex from Mycobacterium tuberculosis. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-60365-5 ...
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Molecular structure of tuberculosis efflux pump reveals how bacteria resist key antibiotic - MSNTuberculosis is the world's leading infectious cause of death, killing more than one million people each year. When the antibiotic bedaquiline was introduced in 2012, it was the first new ...
The first low-resolution structure, aided by docking with AlphaFold2, the artificial intelligence protein structure prediction system, showed the domain that spans the inner membrane of M.
The protein MmpL5 is an efflux transporter, a critical pump that helps the pathogen M. tuberculosis grow by scavenging essential iron. Unfortunately, overexpressed MmpL5 can also pump out ...
At some point, you've probably sat across from a doctor who looked at your tired face and said, “It’s just a viral fever.” ...
Arun Kumar Gupta Environmental pollution today stands as one of the most significant challenges faced by humanity. Its ...
It might look like the scope sitting by a window in the new building’s parasitology suite was situated to give its user a sweeping view of the county’s Overland Avenue operations campus in Kearny Mesa ...
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You’d be excused for being suspicious of these concoctions. Poured into clear-glass one-gallon jars of unregulated ...
And some microbes (usually bacteria) are probiotics – these are similar to ... Epidemiologists track the spread of animal diseases, such as Schmallenberg virus and bovine tuberculosis, and advise ...
Anaerobic bacteria were among the first life forms on Earth and existed at a time when there was no oxygen in the atmosphere.
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