Here, the authors show that the SCFGrr1 complex promotes HAC1 mRNA splicing and translation by degrading the deubiquitinating enzyme Ubp3, thereby maintaining eS7A monoubiquitination to facilitate ...

This month's cover highlights the article Boosting human immunology: Harnessing the potential of immune organoids by Dirk Baumjohann and Maximilian Moll. The review article explores recent advances in ...

ATP-dependent chromatin remodelling proteins represent a diverse family of proteins that share ATPase domains that are adapted to regulate protein–DNA interactions. Here, we present structures of the ...

The cells in our body communicate with each other to coordinate many essential processes, including cell division and the formation of tissues and organs. The Wnt signaling pathway is crucial for cell ...