Another important discovery was an intricate RNA structure near the critical ... detailed map of the translational landscape of HIV-1 infected cells but also a wealth of potential targets for ...

This transmission electron microscopy image shows HIV viral particles (yellow) near the end of the budding process; the cell they’ve infected is in blue. However, viruses like HIV require a living ...

Two research teams led by Warner Greene at the Gladstone Institutes in San Francisco have demonstrated that the vast majority of CD4 T cells in lymphoid tissues, despite their ability to resist full ...

In a ceremony held last month, the 2024 Louisa Gross Horwitz Prize was awarded to Wesley Sundquist, PhD, Leo T. and Barbara K ...

Study findings provide a new gene pathway for potential treatment of the virus affecting millions. Mount Sinai researchers have developed a method to uncover the hidden immune cells that harbor ...

Figure 1: The HIV-1 central DNA flap enhances gene ... higher relative number of integrated vector molecules per cell. The flap structure probably allows the reverse-transcribed genome to be ...

"There is a battle going on in the cell," said Chelico. "HIV also has a protein known as ... and they form a new structure," said Chelico. "APOBEC proteins are part of a natural defense system ...

The use of combination antiretroviral therapy results in a substantial reduction in viremia, a rebound of CD4 + T cells and increased survival for HIV-infected individuals. However, this treatment ...

A new antiretroviral target has been identified that suppresses HIV-1 replication and selectively kills HIV-1-infected cells. HIV-1 is the most common type of HIV. When HIV-1 leaves infected cells, ...