The endocannabinoid system is an active and complex cell signaling network. It involves a combination of endocannabinoids, enzymes, and cannabinoid receptors that help regulate several functions in ...

The discovery of cannabis’s principal active ingredient is the stuff of scientific legend. In the early 1960s, a scientist in Israel named Raphael Mechoulam obtained some high-quality hashish from the ...

The endocannabinoid system is found throughout the brain and body and plays a key role in everything from memory and learning to sleep to social behavior. During prolonged aerobic exercise, the body's ...

In 1964, Israeli scientist Raphael Mechoulam isolated tetrahydrocannabinol, or THC, from a cannabis plant. Hundreds of chemicals exist in cannabis, not just the high-inducing THC and supposed-wellness ...

New research published in Neuroscience provides insight into how chronic treatment with escitalopram, a commonly prescribed antidepressant, can reverse anxiety- and despair-like behaviors in ...

Cannabis, once a symbol of rebellion and counterculture, is now one of the most commonly used recreational substances. The plant’s primary psychoactive compounds, THC (tetrahydrocannabinol) and CBD ...

THC, the psychoactive component of cannabis, binds to receptors in and outside of the brain, causing cells to behave differently. Cannabinoid receptors, named after cannabis, are found in nearly every ...