"This work addresses a long-standing mystery surrounding an enzyme critical for regulating the cell cycle and cell ... companies have eyed cyclin dependent kinase (CDK7) with interest due to ...

This work addresses a long-standing mystery surrounding an enzyme critical for regulating the cell cycle and cell ... companies have eyed cyclin dependent kinase (CDK7) with interest due to ...

Cancer drugs that inhibit CDK7 rapidly shut down pathways responsible for cell proliferation within minutes. For organs to ...

Our findings provide insights into cyclin D1’s role in cell cycle control and oncogenesis beyond RB phosphorylation. Deregulation of cellular proliferation, often mediated by uncontrolled CDKs’ ...

The study also identified a key regulatory mechanism involving cyclin-dependent kinase 2 (CDK2), a protein associated with cell cycle progression. Inertially cycling B cells showed higher CDK2 ...

2023; Shen et al., 2020). Figure 3. LncRNAs modulate the cell cycle of BC cells via interactions with Cyclin/CDK complexes. By Figdraw. Various lncRNAs influence the cell cycle by modulating the ...