Ubiquitin marks proteins for degradation, whereby ubiquitin molecules can be combined in different types and numbers forming ...
To prevent this, cells have developed a sophisticated system to mark unwanted proteins for degradation with a small protein called ubiquitin. Ubiquitin chains Ubiquitin is a cellular tag that marks ...
Researchers have revealed for the first time how a key protein linked to Parkinson's mutates, leads to cell death in the ...
Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...
Speaking to the Walter and Eliza Hall Institute of Medical Research, the study’s author Professor David Komander said: “Our ...
Scientists at deCODE genetics/Amgen have identified associations between bipolar disorder and rare loss-of-function variants ...
A new study has uncovered a molecular mechanism by which rice cells perceive viral infections and initiate antiviral response ...
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Scientists find links between bipolar disorder and rare loss-of-function variants in two genesScientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between bipolar disorder and rare loss-of-function variants in two genes.
The precise regulation of the RIG-I-like receptors (RLRs)-mediated type I interferon (IFN-I) activation is crucial in antiviral immunity and maintaining host immune homeostasis in the meantime. Here, ...
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