Trials evaluating the use of hypertonic saline solutions for resuscitation after traumatic injury have not shown an overall mortality benefit compared with isotonic fluid administration.

A recent single-blind, randomised controlled trial evaluated the efficacy of normal saline nasal irrigation in managing AR ...

Conclusion. There is no evidence that hypertonic saline provides any additional benefit over isotonic crystalloid solutions for trauma resuscitation. Hypertonic saline may be more effective than ...