Ubiquitin marks proteins for degradation, whereby ubiquitin molecules can be combined in different types and numbers forming ...

Researchers say structure reveals many new ways to change PINK1, essentially switching it on, which will be "life-changing" for people with Parkinson’s disease.

To prevent this, cells have developed a sophisticated system to mark unwanted proteins for degradation with a small protein called ubiquitin. Ubiquitin chains Ubiquitin is a cellular tag that marks ...

Discover PINK1 structure offers new hope for Parkinson’s disease treatment by revealing its mitochondrial interactions and ...

This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...

Researchers have revealed for the first time how a key protein linked to Parkinson's mutates, leads to cell death in the ...

WEHI researchers have solved a decades-long mystery by determining the structure of human PINK1, a key protein linked to ...

Speaking to the Walter and Eliza Hall Institute of Medical Research, the study’s author Professor David Komander said: “Our ...

New research provides key insights into the structure and function of PINK1, a protein linked to Parkinson's disease.

Melbourne-based researchers at the Walter and Eliza Hall Institute (WEHI) at the Parkinson's Disease Research Centre have ...