Ubiquitylation is the post-translational modification process by which ubiquitin is attached via an isopeptide bond to lysine residues on a protein. Ubiquitylation consists of three steps ...

Cell signalling articles from across Nature Portfolio Atom RSS Feed Cell signalling is the mechanism by which stimuli are transmitted via a signalling cascade to effector molecules that ...

This protein interacts with immune receptors to signal that a cell is safe and should not be destroyed. When this signaling pathway weakens or fails, the immune system mistakenly targets the body's ...