Study reveals the structure of PINK1 protein, offering fresh hope for Parkinson's patients through potential targeted ...

The method triggers immune responses that inhibit melanoma, triple-negative breast cancer, lung carcinoma, and ovarian cancer ...

Every organism on Earth is a well-oiled machine in its own environment. It makes sense then that every piece of every process ...

For simplicity, they are shown mirror-inverted, so that the Connectase binding channel is visible, and the recognition sequence can be read from left (N-terminus) to right (C-terminus). A and B ...

Nanobubbles (NBs) are tiny gas cavities with diameters around 200 nm that remain stable in solution due to their unique properties, including low buoyancy and negative surface charges. Ammonium ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

For example, DELTEX E3 ligases were reported to ubiquitylate a hydroxyl group on free NAD + and ADP-ribose in vitro, generating a noncanonical ubiquitin ester-linked species. In this report, we show, ...

The network tests for Elden Ring Nightreign have already come and gone, which only means one thing - we're closer than ever to finally getting our hands on some co-op soulslike goodness.

UBE3A is an E3 ubiquitin ligase encoded by an imprinted gene whose maternal deletion or duplication leads to distinct neurodevelopment disorders Angelman and Dup15q syndromes. Despite the known ...

Sequences are ordered lists of objects that follow specific patterns or rules. Each number in the sequence is called a term. Sequences can be classified as arithmetic or geometric. Arithmetic ...