"I was willing to give up my whole life to come out here." The treatment, called a cultivated autologous limbal epithelial cell transplantation -- or CALEC -- can help restore surface corneal ...

Airway epithelial cells act as a physical barrier against environmental toxins and injury, and modulate inflammation and the immune response. As such, maintenance of their integrity is critical.

Compared with women with ASC-US, the results of women with ASC-H on routine Pap are much more likely to have moderate to severe CIN, with estimates ranging widely from 24% to 94%. As a result ...

In contrast, physiological cell shedding allows the renewal of the epithelial monolayer without compromising the barrier function. Here, we investigated the role of live cell extrusion in epithelial ...

Design We developed a mouse model that closely resembles EoE by utilising oxazolone haptenation in mice with transgenic overexpression of an eosinophil poietic and survival factor (interleukin (IL)-5) ...

A new study suggests that never-seen-before stem cells in the human retina can restore vision in mice with a common eye disorder. But more work is needed to translate the treatment to people.

Pulmonary fibrosis is associated with the senescence of alveolar type II epithelial (ATⅡ) cells. Additionally, ATⅡ senescence can lead to a senescence-associated secretory phenotype, which affects ...

Lens epithelial cells (LECs), located on the anterior surface of the lens, are the parental cells responsible for growth and development of the transparent ocular lens. During lens development, LECs ...

A 24-year-old young man presented to us with total limbal stem cell deficiency (LSCD ... underwent limbal biopsy in the healthy contralateral eye and autologous simple limbal epithelial ...

This is a useful report of a spatially-extended model to study the complex interactions between immune cells, fibroblasts, and cancer cells, providing insights into how fibroblast activation can ...