Shorter slow wave sleep and rapid eye movement sleep were associated with decreased volume in Alzheimer disease-vulnerable brain regions.

This system offers single-cell resolution with imaging depths up to 300 microns to enable detailed exploration of densely labelled and deep regions, such as the entorhinal cortex and hypothalamus.

Neuroscientists have produced the largest wiring diagram and functional map of a mammalian brain to date using tissue from a part of a mouse's cerebral cortex involved in vision, an achievement ...

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In the case of the AD fold, they believe tau fibrils begin to form not as a response to Aβ amyloidosis, but rather as a function of aging, since the same AD-tau filaments have been found in the ...

2017). Hyperphosphorylated tau was detected in the locus coeruleus by 6 months of age, prior to its appearance in medial entorhinal cortex or hippocampus. No neurofibrillary tangles, amyloid plaques, ...

From von Economo's work, Allman learned that the unusual cells seemed to reside only in the anterior cingulate cortex (ACC) and one other niche of the human brain, the frontal insula (FI).

Subsequent mediation analysis revealed that the left parahippocampal seed-ventromedial prefrontal cortex functional connectivity mediated the relationship between subjective TP and DD. Our findings ...

This approach revealed that in addition to the dentate gyrus, neurogenesis modulates the cellular profile in the entorhinal cortex and CA regions of the hippocampus. Notably, enhancing neurogenesis in ...