Technological advances empower the modification of NK cells and renewed potential for therapeutic uses in cancer and ...

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

Drug discovery efforts have expanded beyond the traditional approaches of small molecules and antibodies to include cells.

A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body.

"This strategy is also applicable to NK cells generated through different protocols, including those expressing chimeric antigen receptors (CAR), which allows recognizing specific antigens found ...

The patent, entitled "Artificial Immunosurveillance Chimeric Antigen Receptor and Cells Expressing the Same ... and efficacy of CAR-T and CAR-Natural Killer (NK) cells. Key features of the patent ...

In direct killing, the NK cell activation receptor recognizes stress ligands whose expressions ... NK cells expressing CAR can recognize specific antigens expressed on the surface of senescent cells, ...

Poised at the interface of initial bacterial host interactions and in granulomatous lesions, antibodies and Fc receptors expressed on macrophages, neutrophils, dendritic cells, natural killer cells ..

A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates ...