The exact role of a tissue in an organism depends on what types of cells it contains. For example, the endothelial tissue that lines the human gastrointestinal tract consists of several cell types.

A new method can be used to identify factors involved in the specialization of naïve endothelial cells to tissue-specific endothelial cells.

The major interest is in the endothelial cell secretome and the crosstalk between ... we have identified Prox1 transcription factor as an essential regulator of satellite cell differentiation, and our ...