It is indicated for the treatment of wet age-related macular degeneration, macular edema following retinal vein occlusion and myopic choroidal neovascularization.

Myopic Choroidal Neovascularization (mCNV) Select Important Safety Information WARNING AND PRECAUTIONS Endophthalmitis and retinal detachments may occur following intravitreal injections.

Forensic pathology is a specialty that addresses society’s need for accurate certification of natural and nonnatural deaths for public health surveillance and allocation of resources.

The other form of AMD is known as “wet” AMD, in which abnormal blood vessel growth (choroidal neovascularization or CNV) damages vision.

Findings published in The American Journal of Pathology may offer novel strategies for managing and preventing retinal diseases characterized by pathologic neovascularization like retinopathy of ...

Choroidal neovascularization in myopic macular degeneration can cause vision loss, but advances in treatment options may prevent that outcome for many. Learn more about these sight-saving therapies.

In particular, we have sought to define the relationship between endothelial TGF-beta signaling and inflamation, as inflammation is a likely driver of diabetic retinopathy and AMD (Wang et al., 2024).

Graphical AbstractC57BL/6J and Trem2 knockout mice were subjected to laser-induced choroidal neovascularization, a model of choroidal neovascular age-related macular degeneration. Purified bovine ...

C57BL/6J and Trem2 knockout mice were subjected to laser-induced choroidal neovascularization, a model of choroidal neovascular age-related macular degeneration. Purified bovine sulfatide and agonist ...

However, how Treg functions are dysregulated in wet AMD patients and whether Treg-derived IL-10 and TGF-β contribute to the choroidal neovascularization in AMD progression remain to be explored. Our ...

Healthy individuals with an induced transient increase in IOP experienced temporary axial elongation and subfoveal choroidal thinning, regardless of whether they had a refractive error, according ...