"This work addresses a long-standing mystery surrounding an enzyme critical for regulating the cell cycle and cell proliferation ... companies have eyed cyclin dependent kinase (CDK7) with ...

Cancer drugs that inhibit CDK7 rapidly shut down pathways responsible for cell proliferation within minutes. For organs to ...

This work addresses a long-standing mystery surrounding an enzyme critical for regulating the cell cycle and cell proliferation ... companies have eyed cyclin dependent kinase (CDK7) with interest ...

DelveInsight’s, “Glioma Pipeline Insight, 2025” report provides comprehensive insights about 180+ companies and 200+ pipeline drugs in Glioma pipeline landscape. It covers the Glioma pipeline drug ...

In healthy cells, cyclin D1 is expressed during the G1 phase of the cell cycle, where it activates CDK4 and CDK6. Its dysregulation is a well-established oncogenic driver in numerous human cancers.

The Chinese company’s saRNA therapy is intended to increase expression in the p21 tumour suppressor gene and acts as a cyclin-dependent ... works to halt the cell cycle at specific checkpoints ...

The SMAD4/C-MYC/Cyclin D1 axis plays a pivotal role in regulating key aspects of cancer biology, particularly in the context of cell cycle progression, proliferation, and tumor growth. SMAD4 is a key ...