eLife

A differentiable model for optimizing the genetic drivers of synaptogenesis

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...
Scientific Research Publishing

Secure Offline: A Hardware-Bound Cryptographic Framework for Software License Validation in Internet Constrained Educational Environments ()

The system employs HMAC-SHA256 (Hash-based Message Authentication Code using SHA-256) for license integrity verification. SHA-256 refers to the Secure Hash Algorithm producing 256-bit hash values (see ...
Open Heart

Sex differences in the association of social determinants of health and adverse cardiovascular outcomes in patients with atrial fibrillation

Background Despite anticoagulation, patients with atrial fibrillation (AF) experience persistent elevated cardiovascular risk ...
BMJ Open

Using virtual twin-based AI models to detect atrial fibrillation and improve stroke outcomes [TAILOR]: a multicentre prospective cohort study

Introduction Atrial fibrillation (AF) is the leading cause of cardioembolic stroke and is associated with increased stroke severity and fatality. Early identification of AF is essential for adequate ...