Dupilumab in patients with diffuse type 2 CRSwNP had beneficial changes in nasal passage microbiota but did not alter gastrointestinal microbiota.

The drugmaker is already carrying out a second phase 3 trial of Fasenra in CRSwNP – called ORCHID – which isn't due to generate results until September 2023, according the listing for the ...

CRSwNP is often marked by persistent nasal congestion, facial pain, and anosmia, and when asthma coexists, as it frequently does in this patient population, disease burden increases and managing ...

The 408 adults with severe CRSwNP in the randomized, double-blind, multicenter, parallel group phase 3 WAYPOINT trial were symptomatic despite using intranasal steroids, ...

When looking specifically at the dominant cellular pattern, calprotectin levels were markedly higher in the non–EOS-CRSwNP and mixed CRSwNP groups vs the healthy control group: 324.5 (159.7) vs ...

Dublin, Jan. 30, 2024 (GLOBE NEWSWIRE) -- The "Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) - Market Insights, Epidemiology, and Market Forecast - 2032" report has been added to ...

Often associated with type 2 inflammation, CRSwNP is characterised by high levels of IL-5 in nasal polyp tissue and a tendency for nasal polyps to regrow post-surgery due to persistent inflammation.

Most people with a condition known as chronic rhinosinusitis with nasal polyps (CRSwNP) are able to control their symptoms by using medicines that are sprayed into the nose or taken by mouth.

As for the ability of tissue SERPINB10 to be a predictive indicator of postop CRSwNP recurrence, although a link was seen between CRSwNP recurrence and tissue eosinophil percentage (odds ratio [OR ...

The approval in adolescent patients was based on evidence from the phase 3 SINUS-24 and SINUS-52 trials (ClinicalTrials.gov Identifier: NCT02912468 and NCT02898454, respectively), which compared ...

CRSwNP is a chronic disease of the upper airway, driven in part by type 2 inflammation, that obstructs the sinuses and nasal passages. It can lead to breathing difficulties, ...