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The drugmaker is already carrying out a second phase 3 trial of Fasenra in CRSwNP – called ORCHID – which isn't due to generate results until September 2023, according the listing for the ...
Dupilumab in patients with diffuse type 2 CRSwNP had beneficial changes in nasal passage microbiota but did not alter gastrointestinal microbiota.
A survey of ENT clinicians reveals variability in managing chronic rhinosinusitis with nasal polyps, including steroid ...
Chronic Rhinosinusitis With Nasal Polyps and Asthma: Understanding the Connection and Treatment Gaps
Chronic rhinosinusitis with nasal polyps increases the likelihood of developing coexisting conditions, such as asthma, underscoring the need for more effective, comprehensive treatments.
CRSwNP is often marked by persistent nasal congestion, facial pain, and anosmia, and when asthma coexists, as it frequently does in this patient population, disease burden increases and managing ...
CRSwNP is a chronic disease of the upper airway, driven in part by type 2 inflammation, that obstructs the sinuses and nasal passages. It can lead to breathing difficulties, ...
The 408 adults with severe CRSwNP in the randomized, double-blind, multicenter, parallel group phase 3 WAYPOINT trial were symptomatic despite using intranasal steroids, ...
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China’s NMPA approves GSK’s Nucala for CRSwNP treatmentOften associated with type 2 inflammation, CRSwNP is characterised by high levels of IL-5 in nasal polyp tissue and a tendency for nasal polyps to regrow post-surgery due to persistent inflammation.
Most people with a condition known as chronic rhinosinusitis with nasal polyps (CRSwNP) are able to control their symptoms by using medicines that are sprayed into the nose or taken by mouth.
The approval in adolescent patients was based on evidence from the phase 3 SINUS-24 and SINUS-52 trials (ClinicalTrials.gov Identifier: NCT02912468 and NCT02898454, respectively), which compared ...
As for the ability of tissue SERPINB10 to be a predictive indicator of postop CRSwNP recurrence, although a link was seen between CRSwNP recurrence and tissue eosinophil percentage (odds ratio [OR ...
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