Lipid nanoparticles, or LNPs, are best known as the delivery system used in the COVID-19 mRNA vaccines given to billions of people worldwide. Scientists are now exploring their potential far beyond ...

Better mRNA release inside cells boosts vaccine and gene editing performance, enabled by redesigned lipid molecules that grip ...

Lipid nanoparticles (LNPs) act as carriers for mRNA and CRISPR payloads across a wide range of therapeutic applications, from cancer to inflammatory and genetic diseases. The same delivery system used ...

Lipid nanoparticles, or LNPs, best known as the delivery vehicle for the COVID-19 mRNA vaccines received by billions of people, are now at the center of a much larger medical revolution. Researchers ...

Since the COVID-19 pandemic, mRNA vaccines have gained attention as a next-generation pharmaceutical technology. mRNA therapeutics work by delivering genetic instructions that enable cells to produce ...

Inspired by a rare immune disorder, researchers headed by a team at Columbia University have created an antiviral with an mRNA delivery system that displays broad activity against Zika virus, SARS-CoV ...

Discover how circular RNA technology enhances gene expression by up to 50-fold in eye treatments, surpassing traditional ...

A new preclinical study by Mass Eye and Ear investigators showed that a novel mRNA-based therapy may be able to prevent blindness and scarring from proliferative vitreoretinopathy (PVR) following a ...

Researchers found that the stereochemistry of lipids like ALC-315 affects mRNA drug safety and efficacy, offering a path to better, safer LNP-based therapies. To deliver therapeutic nucleic acids like ...