The 49ers opened their preseason with a 30-9 loss against the Denver Broncos from Levi's Stadium in Santa Clara, Calif. While there was some good and bad for the 49ers from the preseason opener, most fans just wanted a look at some of the fresh faces and for San Francisco to get out of the contest mostly in one piece.

San Francisco 49ers wide receiver Brandon Aiyuk hasn't played since Oct. 20 because of a significant knee injury that limited him to just seven games last season, but fans might not have to wait too long into the 2025 campaign to see him take the field.