Canada has an opportunity to prevent sustained Clade I mpox transmission, but only if decisive action is taken now.

As viral vaccines are increasingly used to meet global health needs, the pharmaceutical industry is manufacturing larger ...

Monkeypox virus (MPXV), which can cause monkeypox (MPX), is a zoonotic enveloped dsDNA virus that belongs to the orthopoxvirus genus of the Poxviridae family. There are two clades of the Monkeypox ...

Poxviruses are a family of large, double-stranded DNA viruses, which include variola virus (smallpox), monkeypox virus, and others, that infect both humans and animals. These viruses are unusual ...

Varicella is caused by varicella-zoster virus (VZV), an enveloped dsDNA virus responsible for varicella (chickenpox) and herpes zoster (shingles). VZV is one of eight herpesviruses known to infect ...

are used to translocate double-stranded DNA (dsDNA) into preformed capsids (proheads) of bacterial viruses and certain animal viruses. Here, we describe the motor that packages the dsDNA of the ...

Monkeypox virus (MPXV) is a zoonotic enveloped dsDNA virus that can cause monkeypox (MPX). It is a member of the Poxviridae family and belongs to the orthopoxvirus genus. The monkeypox virus was ...

Therefore, the existence of a cytoplasmic dsDNA sensor has been proposed ... antiviral state that inhibits the replication of diverse viruses, including the invading pathogen.

The vast abundance of viruses within natural ecosystems is paralleled by their extraordinary diversity. It is likely that dsDNA viruses also comprise Earth’s largest pool of unknown and novel genetic ...

Their genome is unusually large. One isolate, PBCV-1, for example, (genome size = 330744 bp dsDNA) codes for ~375 proteins, nearly half of which resemble proteins of known function. The genomes of ...