The 49ers likely have no intention of playing starter Christian McCaffrey in the preseason, backup Isaac Guerendo is out for ...

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

Christian McCaffrey, Kyren Williams, & Najee Harris have carried heavy workloads in their NFL careers. Injury concerns will raise caution in fantasy football.

San Francisco 49ers running back Christian McCaffrey explained why he sometimes feels uneasy sleeping in a hotel room amid ...

The San Francisco 49ers could use more capable running backs on their roster and signing Jeff Wilson Jr. gives them another.

The 49ers are limiting Christian McCaffrey's training camp reps to keep the running back healthy for the season opener and ...

Christian McCaffrey enters the 2025 season as a polarizing figure in fantasy football discussions. Despite his undeniable ...

The 49ers started 3-4 and traded for Christian McCaffrey, finishing 13-4 and reaching the conference championship game. They started 5-3 last season and ended up 12-5, reaching the Super Bowl.

When the 49ers offense is healthy, it's one of the best in the NFL. Unfortunately, their offense wasn't healthy last year, and it isn't healthy now.

Evaluating the risk-factors of Christian McCaffrey and his ability to be drafted in the first round of your fantasy football ...

Christian McCaffrey has some dad guilt as football preseason heats up. The San Francisco 49ers running back has been busy in ...

On McCaffrey’s 8-yard run to give the 49ers a 21-3 lead in the second quarter, he took a toss left from Purdy, was stacked up immediately in the backfield, but somehow picked his way through ...