A team of researchers from the University of Aberdeen has uncovered, for the first time, how genes linked to autism and ...
By analyzing over 213,000 developing human brain cells, researchers show that many autism risk genes act through the ECM. These genes are active in specific cell types and developmental windows, ...
In cell and animal models of amyotrophic lateral sclerosis (ALS), the expression of toxic dipeptides in neurons led to changes in the extracellular matrix (ECM) as a protective response. The authors ...
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Remodeling the tumor microenvironment to unlock CAR-T cell potential
Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor ...
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