The tiny shell protecting the HIV virus resembles a slightly rounded ice cream cone, but there is nothing sweet about it.
The canonical rAAV vector holds ≦ 4.7 kb single-stranded (ss) DNA within a 60-protein icosahedral capsid, and tropism is chosen from 13 known natural and supplementary unique hybrid serotypes enabling ...
- Agreement grants Astellas rights to employ Sangamo’s novel proprietary capsid, STAC-BBB, for up to five potential neurological disease targets - Sangamo to receive a $20 million upfront license fee ...
The FDA granted priority review, with a decision expected by June 19, 2025. LEN represents a novel class of HIV therapies by targeting the viral capsid, a multifunctional protein essential for HIV ...
Apertura Gene Therapy, a biotechnology company developing next-generation AAV capsids for delivering genetic medicines, today ...
A novel bioengineering strategy utilizing peptide display technology on the AAV1 capsid has successfully generated next-generation viral vectors with significantly enhanced specificity and efficiency ...
RICHMOND, Calif.--(BUSINESS WIRE)--Sangamo Therapeutics, Inc. (Nasdaq: SGMO), a genomic medicine company, today announced preclinical data from its proprietary adeno-associated virus (AAV) capsid ...
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