Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...

Due to the inherent anisotropy of the optical PSF, the HR lateral images naturally serve as the rational gold standard for enhancing the axial resolution of the raw data. The unpaired lateral and ...

There is a growing demand for non-invasive insights into the complex three-dimensional subcellular dynamics within living tissues at the frontier of biological research. Professor Xi Peng's group at ...

In life sciences, confocal fluorescence microscopy (CFM) is widely regarded for producing high-resolution cellular images. However, it requires fluorescent staining, which poses risks of ...

Both images show individual red blood cells. The one on the right, produced by STED, more clearly shows the Piezo1 proteins (in green), which are a mechanical calcium channel and play a crucial role ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

Scientists use confocal microscopy to study intracellular organization, structures, and dynamics in 3D. Selecting a microscope platform for a research project can be challenging because different ...

The inverted Nikon spinning disk confocal microscope is equipped with four laser lines (405, 488, 561, and 647 nm), 4x-40x air objective lenses, and 60x NA1.40 and 100x NA1.45 oil objective lenses.

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