Researchers have revealed for the first time how a key protein linked to Parkinson's mutates, leads to cell death in the ...

A new study has uncovered a molecular mechanism by which rice cells perceive viral infections and initiate antiviral response ...

Researchers say structure reveals many new ways to change PINK1, essentially switching it on, which will be "life-changing" for people with Parkinson’s disease.

Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...

Such modifications include ubiquitination and covalent attachment of ubiquitin-like molecules (e.g., SUMO or ... modifications regulate cell cycle proteins that could disrupt TGF-β signaling(Liu et al ...

In this process, bacteria are labeled as foreign bodies within cells, thereby signaling their destruction by the cellular ...

My group focuses on understanding cell signaling pathways primarily linked with the ubiquitin and autophagy systems and frequently altered in diseases, including neurodegenerative disease. To this end ...

Breast cancer is one of the leading causes of mortality among women worldwide. Tumor necrosis factor α-induced protein 3-interacting protein 1 (TNIP1) is a ubiquitin-binding protein that is widely ...