Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world's population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a ...

Structure discovered for promising tuberculosis drug target Date: October 25, 2012 Source: Johns Hopkins Medicine Summary: Researchers have figured out the three-dimensional shape of the protein ...

Tuberculosis (TB) bacteria infect a third of the world's population and the disease kills 1.8 million people annually. ... Structure of tuberculosis drug target determined ...

Scientists have uncovered a promising new pathway in the development of tuberculosis drugs, describing what they call a newly-discovered “keyhole” that can be targeted to starve tuberculosis ...

In this way, T-boxes facilitate basic functioning in bacteria, including many pathogens such as M. tuberculosis and Bacillus anthracis, which causes the deadly anthrax disease.

Tuberculosis (TB) is one of the ... Suicide system in tuberculosis bacteria might hold key to treatment ... image: This is the high-resolution structure of the toxin-antitoxin system. view more .

Rutgers University scientists have determined the three-dimensional structure of the target of the first-line anti-tuberculosis drug rifampin. They have also discovered a new class of potential ...

The bacteria that cause tuberculosis need iron to survive. Researchers at the University of Zurich have now solved the first detailed structure of the transport protein responsible for the iron ...

A new study published in Biochemistry sheds light on how bacteria regulate their genes, challenging long-held assumptions ...

Histone-like HU proteins play roles in chromatin architecture and DNA-dependent processes in bacteria. Here, the authors describe the crystal structure of the DNA-binding domain of HU from ...

A new methodology developed by researchers at Rice and Rutgers universities could help scientists understand how and why a biochemical network doesn’t always perform as expected. To test the ...

Tuberculosis (TB) remains one of the most lethal infections in the world, resulting in over 1.5 million deaths each year. While it is currently curable, the bacteria responsible for it are fast ...