Tuberculosis is the world's leading infectious cause of death, killing more than one million people each year. When the antibiotic bedaquiline was introduced in 2012, it was the first new ...

In 2007, Eltis' group discovered that tuberculosis bacteria grow on cholesterol and that this is important for causing disease. "Many bacteria, like humans, grow using glucose, a type of sugar.

Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world's population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a ...

Tuberculosis (TB) bacteria infect a third of the world's population and the disease kills 1.8 million people annually. ... Structure of tuberculosis drug target determined ...

This bacterial structure explains why TB can withstand harsh environmental conditions and resist many standard antibiotics. ... Tuberculosis sits at the intersection of medical science, ...

Cryo-EM structure of the MmpL5-MmpS5-AcpM complex from Mycobacterium tuberculosis. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-60365-5 ...

The first low-resolution structure, aided by docking with AlphaFold2, the artificial intelligence protein structure prediction system, showed the domain that spans the inner membrane of M.

Scientists have uncovered a promising new pathway in the development of tuberculosis drugs, describing what they call a newly-discovered “keyhole” that can be targeted to starve tuberculosis ...

Tuberculosis, the world’s oldest and deadliest pandemic, has been plaguing us for well over 4,000 years, with a relative of TB bacteria detected since the dinosaur age, and an ancestor having ...

Ocular or eye tuberculosis is a rare eye infection that involves the same bacteria as TB in the lungs. Treatment can take several months, but it is usually effective.