When German biologist and doctor Robert Koch announced in 1882 that he had discovered the bacterial cause of tuberculosis, he said, "If the number of victims which a disease claims is the measure ...

John Green’s new book, Everything Is Tuberculosis, reveals how social injustice sustains the disease, despite available cures and vaccines.

Early diagnosis and treatment of active Tuberculosis is utmost priority, but identifying the latent TB, especially among the ...

Tuberculosis lives and thrives in the lungs. When the bacteria that cause the disease are coughed ... droplets and measured ...

Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas. A characteristic feature of tuberculosis (tubercle = nodular swelling) is the formation of granulomas. These nodular tissue ...

They engineered a strain of M. tuberculosis carrying a triple kill switch, which uses three independent molecular mechanisms to kill the bacteria. Even in severely immunocompromised mice ...

The study, published March 7 in PNAS, revealed for the first time that tuberculosis bacteria don't passively endure these transitions but actively engage hundreds of genes to adapt and survive.

Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models. Nature Microbiology , 2025; 10 (2): 482 DOI: 10.1038/s41564-024-01913-5 ...