Amino acids are the building blocks that form polypeptides and ultimately proteins. Consequently, they are fundamental components of our bodies and vital for physiological functions such as protein ...

'Inheritance through homology' is the most common and generally more accessible approach to function prediction, but orthology should be established where possible to improve confidence in predictions ...

The cell nucleus is the site of many important biological functions of the eukaryotic cell. These processes include transcription, replication, splicing and ribosome biogenesis. The effect of these ...

G protein-coupled receptors (GPCRs) are targeted by ∼30–40% of marketed drugs, and their key roles in normal physiology and in disease demonstrate that an understanding of their structure and function ...