A deficiency of one or more components of the prothrombin complex may complicate many clinical states: cirrhosis; hepatitis; biliary obstruction; malabsorption; childbirth; and the preoperative and ...
PARAMUS, N.J., July 26, 2023 – Octapharma USA today announced that Balfaxar ® (prothrombin complex concentrate, human-lans; marketed in Europe and Canada as octaplex ®) has received U.S. Food and Drug ...
RARITAN, N.J., July 2, 2013 /PRNewswire/ -- Janssen Research & Development, LLC (Janssen) announced today results of an open label, single-center, parallel group study showing that a type of ...
The 94.3% efficacy of the Octapharma product was just a shade ahead of the 94.2% measured in a comparative product, Kcentra. Results of a Phase III study (LEX-209) of the safety and efficacy of ...
Approximately 15% of patients undergoing cardiac surgery experience excessive bleeding that leads to depletion of clotting factors. Transfusion of frozen plasma is the standard treatment for excessive ...
Among over 300 patients with the highest trauma level activation, the absolute difference in median total 24-hour blood product consumption between the 4F-PCC and placebo groups was 0.2 U (95% CI ...
Thirteen patients with liver disease and an abnormal prothrombin time refractory to vitamin K therapy were studied (Tables 1 and 2). None of the patients were actively bleeding, and none had received ...
Blood products, such as prothrombin complex concentrate, should be used only when the international normalized ratio (INR) is at least 1.5 and the patient has major bleeding (e.g., intracranial ...
TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech ...
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