Platelets play a crucial role in hemostasis; activating and aggregating to arrest bleeding following vascular injury. Platelet activation is a complex and dynamic process, involving the co-ordination ...

Coronary heart disease and stroke, two of the leading causes of death in the United States, are diseases associated with heightened platelet reactivity. A new study in humans suggests an underlying ...

Coronary heart disease and stroke, two of the leading causes of death in the United States, are diseases associated with heightened platelet reactivity. A new study in humans suggests an underlying ...

Researchers led by Professor Steve Watson and Dr Eleyna Martin from the Institute of Cardiovascular Sciences at the University of Birmingham have delivered a breakthrough for thrombosis researchers, ...

Future Microbiol. 2013;8(11):1431-1451. Bacterial contact with the platelets is a key event for the pathogenesis of sepsis, as deduced from the correlation between sepsis outcome and decreased ...

Blood platelets have a receptor for macromolecular adhesive glycoproteins, located on a heteroduplex membrane glycoprotein complex (GPIIb/IIIa) that only becomes "exposed" when platelets are activated ...

Previous studies have shown that receptor-interacting protein kinase 3 (RIP3) is involved in many important biological processes, including necroptosis, apoptosis, and inflammation. Here we show that ...

Nieman's research program seeks to define the assembly of receptor complexes and determine how they work together at the molecular level to mediate physiological responses. Since 2007, his laboratory ...

Immune thrombocytopenia (ITP) is a rare blood disorder in which the immune system mistakenly attacks and destroys platelets. Platelets are small blood cells that play a critical role in helping your ...

Q: My platelets were slightly elevated on my blood test. What can cause this? A: Platelets are part of how our body forms clots to stop bleeding. They are produced in the bone marrow by cells called ...