The Sooners took an early lead, but late pitching struggles allowed South Carolina to take game two of the series on Saturday.
The Sooners' all-time winningest coach with 851 victories, Semore guided OU to five CWS trips and 14 straight NCAA Tournaments and had his jersey retired last spring.
Oklahoma (14-1) swept a three-game series against Sam Houston (3-12) 6-5, 7-3 and 9-7 at L. Dale Mitchell Park.
He's the winningest head coach in program history. More: Why OU baseball retiring former coach Enos Semore's jersey was 'really important' "We are deeply saddened by the passing of Coach Enos ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results