The addition of chimeric antigen receptors (CAR) results in NK cells that target antigens found on tumors. Equally, edits that affect the tumor microenvironment or cell persistence will be ...

Technological advances empower the modification of NK cells and renewed potential for therapeutic uses in cancer and autoimmunity.

A T cell, for instance, has a lock-shaped structure on its surface into which ... cells from AML patients than NK cells that either only carried the CAR receptor or lacked the immune checkpoint ...

Dendritic cells (DC) 'prime' tumor antigen-specific cytotoxic T lymphocytes; thus, we investigated whether DC might also trigger the innate, NK cell-mediated anti-tumor immunity. In mice with MHC ...

But T-cells aren't the only option for cell therapy. Promising work is being done with natural killer, or NK cells, a different kind of immune system cell that could work even better in some ways.

A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates ...

Triggering receptors expressed on myeloid cells (TREMs) are a cell surface receptor family found on granulocytes, monocytes, macrophages, and dendritic cells—as well as other myeloid cells in general.

Leukocytes are particularly well suited for these tasks because they can completely reorganize their structure in a matter of minutes in response to surface receptor ... target cells: Cytotoxic T ...