This transmission electron microscopy image shows HIV viral particles (yellow) near the end of the budding process; the cell they’ve infected is in blue. However, viruses like HIV require a living ...
To become infectious, HIV has to undergo a maturation process, which involves a rearrangement of the matrix proteins (red). In an immature virus particle, the matrix proteins form a lose lattice ...
In a ceremony held last month, the 2024 Louisa Gross Horwitz Prize was awarded to Wesley Sundquist, PhD, Leo T. and Barbara K ...
HIV inserts its genes into the host cell's nucleus in an unusual way ... So we can't really get a good structure of it." Yang, then a graduate student at the University of Pittsburgh, wanted ...
Two research teams led by Warner Greene at the Gladstone Institutes in San Francisco have demonstrated that the vast majority of CD4 T cells in lymphoid tissues, despite their ability to resist full ...
"There is a battle going on in the cell," said Chelico. "HIV also has a protein known as ... and they form a new structure," said Chelico. "APOBEC proteins are part of a natural defense system ...
Protein crystallization at the SER-CAT beamline at Argonne’s Advanced Photon Source proved key to the discovery of a new HIV vaccine candidate.
A new antiretroviral target has been identified that suppresses HIV-1 replication and selectively kills HIV-1-infected cells. HIV-1 is the most common type of HIV. When HIV-1 leaves infected cells, ...