Immunocore’s big swing for a functional HIV cure has cleared its first hurdle. | Immunocore’s big swing for a functional HIV ...
Protein crystallization at the SER-CAT beamline at Argonne’s Advanced Photon Source proved key to the discovery of a new HIV vaccine candidate.
To become infectious, HIV has to undergo a maturation process, which involves a rearrangement of the matrix proteins (red). In an immature virus particle, the matrix proteins form a lose lattice ...
In a ceremony held last month, the 2024 Louisa Gross Horwitz Prize was awarded to Wesley Sundquist, PhD, Leo T. and Barbara K ...
HIV inserts its genes into the host cell's nucleus in an unusual way ... So we can't really get a good structure of it." Yang, then a graduate student at the University of Pittsburgh, wanted ...
"There is a battle going on in the cell," said Chelico. "HIV also has a protein known as ... and they form a new structure," said Chelico. "APOBEC proteins are part of a natural defense system ...
This transmission electron microscopy image shows HIV viral particles (yellow) near the end of the budding process; the cell they’ve infected is in blue. However, viruses like HIV require a living ...
Two research teams led by Warner Greene at the Gladstone Institutes in San Francisco have demonstrated that the vast majority of CD4 T cells in lymphoid tissues, despite their ability to resist full ...
A new antiretroviral target has been identified that suppresses HIV-1 replication and selectively kills HIV-1-infected cells. HIV-1 is the most common type of HIV. When HIV-1 leaves infected cells, ...