Inherited insulin resistance syndromes arise predominantly from mutations in the insulin receptor (INSR) gene, though variants in downstream signalling components and regulatory loci also contribute.

A proof-of-concept study finds that donated insulin-producing cells can be genetically modified to avoid provoking the recipient's immune system. Reading time 3 minutes A new case study offers a ...

Researchers identify genetic markers that predict the rate of β-cell failure in type 1 diabetes, facilitating earlier, personalized care strategies Type 1 diabetes (T1D) is an autoimmune condition ...

In a demonstration that could help pave the way for gene therapies with fewer side effects, several human cell types have been genetically modified with protein nanoparticles designed at University of ...

An estimated 9.5 million people all over the world live with type 1 diabetes, wherein the beta cells in their pancreas cannot produce enough insulin to keep blood glucose in check. 1 In the long run, ...