Immunofluorescence image showing S100A11 (green) localization to focal adhesions and actin stress fibers in a HeLa cell. Microtubules are labeled in red. Researchers at Kanazawa University report in ...

Since its initial discovery, ARF has been described to have a prevalent nucleo-nucleolar localization. More recently, ARF has been reported to localize also in the cytoplasm mainly associated to ...

The adhesion of a cell to a surface is essential for many cellular processes, including the cell cycle. This article will describe recent studies which have expanded our knowledge of the role of focal ...

Researchers have developed a new form of microscopy that allows them to observe the formation and evolution of cell membrane focal adhesions. Focal adhesions are large specialized proteins that are ...

Focal adhesions are known as signaling platforms broadcasting the information of the biochemical and physical qualities of the extracellular matrix into intracellular signaling cascades. However, ...

Scientists from the Mechanobiology Institute, Singapore (MBI) at the National University of Singapore have discovered the universal building blocks that cells use to form initial connections with the ...

The fight against cancer often begins with uncovering hidden players, and this study reveals one such key player: an unexpected class of abbreviated N-glycans. These molecules, upregulated in cancer ...

“Cell migration is required and essential for metazoan development, tissue regeneration and repair, as well as in immune surveillance. Many diseases such as cancer, fibrosis, and inherited ...