If gene therapies are to realize their enormous therapeutic and commercial potential, they will need well-designed delivery vehicles—and lots of them. In the near term, most of these vehicles will ...

Kristofer Mussar, PhD, is COO of VectorBuilder and MD of VectorBuilder GmbH, leading global operations and innovation in gene delivery. What if business leaders approached strategy the way scientists ...

In the episode, we’re talking about vector design and delivery for gene therapies. The field of cell and gene therapies is advancing, but there are still challenges with delivery vectors that need to ...

Jessica Nance, MD, MS, discusses maximizing gene therapy efficiency by selecting vectors for gene size, tissue targeting, and low exposure, and focusing on precise promoters for expression. This is a ...

Adeno-associated viruses have become popular vectors for the delivery of gene therapies. But, despite their relatively safe profile, they can trigger some unwanted immune responses, which may reduce ...

Circular plasmid DNA has traditionally been used as a stable and efficient vector for gene expression and HDR-mediated gene insertion. These vectors typically carry at least one antibiotic-resistant ...

Ad5 vectors are the most commonly used adenovirus vector. Ad5 vectors transduce a wide range of cell types. They utilize the Coxsackie-Adenovirus Receptor (CAR) to enter cells. Transduction efficiency ...

Vector BioPharma AG (Vector BioPharma), a biopharmaceutical company aiming to transform the safety, efficacy, and specificity of drug delivery to improve treatments for patients, today announced that ...

MILAN--(BUSINESS WIRE)--On the heels of AAVantgarde closing a Series B financing round, AGC Biologics announced a new manufacturing agreement with the biotechnology company, marking AGC Biologics’ ...