Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

A new study published in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center ...

DNA Repair Pathways in Clinical Practice: Lessons From Pediatric Cancer Susceptibility Syndromes. If you have the appropriate software installed, you can download article citation data to the citation ...

A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer ...

The researchers focused on Fanconi anemia, a rare inherited disorder characterized by a failure to repair specific types of DNA damage. In this condition, the two strands of DNA literally become stuck ...

Large-scale drug atlas uncovers new genome editing modulators and potential therapeutic strategies for DNA repair-deficient cancers ...

Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...

Rb1 loss may serve as a predictive biomarker to guide new targeted therapies for select breast cancers resistant to standard ...

New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral ...