Individual components, including the template, primers, polymerase, dNTP levels, and cycling conditions, can impact the overall PCR reaction. Explore how these ...

The COVID-19 pandemic led to many changes. Among them is universal familiarity with a molecular diagnostic technique that was largely unknown outside clinical use. The polymerase chain reaction — or ...

PCR is a technique used to amplify target DNA in a sample. It’s a well-known method that has undergone numerous modifications to enhance its capabilities. This year, it’s turning 40 years old. PCR has ...

A polymerase chain reaction (PCR) test detects genetic material from a pathogen or abnormal cell sample. Ways of collecting samples include a nasal swab, a saliva swab, or taking a sample of blood.

Quantitative PCR (qPCR) instruments that operate in real-time need high sensitivity and the most favorable signal-to-noise ratio possible. The bandwidth of excitation, center wavelength (CWL) and ...

In the summer of 1984, Henry Erlich, Glenn Horn, Randy Saiki, and myself were working on developing a DNA test for sickle cell anemia (SCA) at Cetus Corp. SCA is an autosomal dominant disease caused ...