Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that ...

Men tend to lose the Y chromosome from their cells as they age. But because the Y bears few genes other than for male determination, it was thought this loss would not affect health. But evidence has ...

Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene ...

Human sex chromosomes originated from a pair of autosomes, the ordinary or non-sex chromosomes that contain the majority of our genome and come in identical pairs. That ancestral pair of autosomes ...

Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they ...

Three specific genes on chromosome 21 drive widespread brain changes in Down syndrome, uncovering a new framework for ...

The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...

The Stowers Institute's Workman Lab has shed new light on a novel histone acetyltransferase protein complex called ATAC. Acetyltransferases are enzymes that introduce a new acetyl functional group ...

Two new studies of the evolutionary history of the Y chromosome show that, contrary to popular (if not scientific) belief, the male is not at risk of dying out. The Y chromosome which, among other ...

AMES, Iowa – A new study led by an Iowa State University scientist sheds light on how organisms have evolved to address imbalances in sex chromosomes. The study looks at a species of softshell turtle, ...