How do we “name” a cell and assign its identity? How do we know that we are all talking about the same cells? How do we agree on what it takes to confidently correlate previous with current research ...

This technology has vast potential to help patients but remains underutilized and underappreciated. The tools are there. What’s lacking are harmonized controls, regulatory guidelines and database ...

Around the same time, Mack Fulwyler, an engineer working at Los Alamos National Laboratory, needed to separate particles, so he drew on existing techniques to create droplets to separate cells from a ...

The identification of reliable biomarkers from peripheral blood is crucial for improving disease diagnosis and monitoring. Spectral flow cytometry has emerged as a powerful tool for high-dimensional ...

Scientists prepare samples as single cell suspensions and labels components of interest with fluorescent antibodies or other probes. The cytometer uses pumps to draw the sample through tubing to ...

Since the 1950s, researchers have used flow cytometry to characterize in immune and other cell types by detecting proteins with antibodies that are linked to fluorescent probes and later also ...

Immunophenotyping helps doctors diagnose and classify specific blood cell cancers, like leukemia and lymphoma, as well as other diseases. Immunophenotyping is a lab test doctors use to identify and ...

Flow cytometry, invented in the 1950s, uses antibodies linked to fluorescent probes to detect cell surface and intracellular proteins. Although able to achieve single-cell sensitivity, the method is ...

Flow cytometry offers practical advantages for real-time monitoring of CAR T cell expansion, persistence, and toxicity risk in aggressive large B-cell lymphoma patients. Early CAR T cell expansion is ...

Two unique case reports highlight the diagnostic challenges and critical importance of comprehensive immunophenotyping in cases of T-cell acute lymphoblastic leukemia/lymphoma that present without ...