Industry is adapting to the increasing complexity and poor solubility and bioavailability of molecules in the pipeline. Poor solubility and low bioavailability have hindered the development pipeline ...
A large share of medicines developed today may never reach patients for a surprisingly simple reason: they cannot dissolve well enough in water. For most treatments, the oral route remains the gold ...
When it comes to supplements, absorption matters just as much as the dosage. You could be taking the most potent multivitamin or mineral supplement, but if your body can’t absorb it properly, it won’t ...
(Beyond Pesticides, July 23, 2024) In analyzing the interactions between neonicotinoid pesticides (NNPs) and microplastics (MPs), a recent study in The Science of The Total Environment finds that ...
I drink a full glass of milk every day and eat cheese, but still, I am deficient in calcium. I include iron-rich foods in my diet to meet my daily requirement of iron, but I am still anemic. It is ...
Upon ingestion, the new Enzian dosage form resides in the stomach for several hours and steadily delivers drug into the blood. This enables enhanced effectiveness of many life-saving drug therapies.
Want to improve the nutritional benefits of your favourite foods? You may need to start thinking about bioavailability… We all want to get the most out of the food we eat, but there’s much more to ...
Marketed formulations of extended phenytoin sodium -- long a difficult medication to titrate because of its unique absorption and saturable elimination pharmacokinetics -- may not be bioequivalent, ...
Although efforts have been made to improve solubility, many poorly soluble drugs still reach the market. Peter Nielsen discusses new developments in solubilisation technology, which could help those ...
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