B-cell activating factor (BAFF) is a key regulator of B-lymphocyte development. Its biological role is mediated by the specific receptors BCMA, TACI and BAFF-R. We have determined the crystal ...
B-cell-activating factor (BAFF) is a member of the tumour-necrosis factor (TNF) family. BAFF is a trimeric membrane-bound or soluble factor that binds to three receptors — BCMA (B-cell maturation ...
Nat Clin Pract Neurol. 2008;4(10):557-567. BCMA Stimulates plasma cell survival and IgM production TACI mRNA is upregulated in the brain and monocytes of patients with MS; TACI is produced by ...
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