The 'double receptor' hypothesis (proposed 20 years ago) posited that protein and ganglioside receptors on the neuronal plasma membrane ... for the entry of BoNT/B into cells and support the ...

Moreover, the clonal expansion and long life of some antigen-primed cytotoxic lymphocytes and plasma ... receptor repertoires. Instead of the V(D)JC composition of immunoglobulin-based B cell ...

demonstrating rapid and sustained degradation of IgE in plasma and on IgE B cell receptors. S‑8484 also demonstrated efficacy in animal models of allergic disease. Designed using protein ...